GenoSmart
Develops a novel diagnostic tool
Sample-to-Result
Sample-to-Result
Point-of-Care
Point-of-Care
Cost-Effective
Cost-Effective
Miniaturize-Enthalpy-Meter (MEM)
Miniaturize-Enthalpy-Meter (MEM)
- Portable
- Point-of-Care
- Sensitive
- Sample-to-Result
- Cost-Effective
- Rapid
GenoSmart develops a novel and proprietary highly versatile bio-electronic molecular diagnostic device termed “Miniature Enthalpy-Meter (MEM)”, for the rapid and accurate diagnosis of pathogens such as: antibiotic resistant bacteria, pandemic viruses and bio-terror agents. Using this technology, we develop a rapid, affordable and easy-to-use diagnostic device for any site of need. The MEM platform detects the minute change in the kinetic energy of molecules, i.e. enthalpy rich specific molecular interactions such as DNA hybridization, enzyme-substrate reactions and antibody-antigen binding within minutes.
GenoSmart has also developed a proprietary, cutting-edge, highly adaptable automatic nucleic acid purification system termed “Automated Nucleic Acid Extraction” (ANAE) device. The ANAE rapidly (within minutes) and efficiently purifies DNA or RNA from any source, be it biological, gel electrophoresis or other, in one automatic step. According to need, the separation process can be readily fitted with any market-accepted method such as bead, column or affinity based (or combined). Ensuing extraction, product can be post-processed by several enzymatic steps with temperatures ranging between sub-ambient to denaturation, to yield highly specific purified products. All ANAE processes are performed rapidly and automatically from start-to-finish.
GenoSmart has also developed a proprietary, cutting-edge, highly adaptable automatic nucleic acid purification system termed “Automated Nucleic Acid Extraction” (ANAE) device. The ANAE rapidly (within minutes) and efficiently purifies DNA or RNA from any source, be it biological, gel electrophoresis or other, in one automatic step. According to need, the separation process can be readily fitted with any market-accepted method such as bead, column or affinity based (or combined). Ensuing extraction, product can be post-processed by several enzymatic steps with temperatures ranging between sub-ambient to denaturation, to yield highly specific purified products. All ANAE processes are performed rapidly and automatically from start-to-finish.
The MEM merged with the ANAE device, allows rapid, cost effective Sample-To-Result diagnosis in any medical setting, from medical laboratories to point-of-care, regardless of environmental conditions and level of staff training.
Currently, solutions are developed for two major pandemics that rapidly spread through-out the world, namely COVID-19 and antibiotic resistant bacteria (specifically, Carbapenemase Producing Bacteria -CPE- that populate patient’s gut).
Currently, solutions are developed for two major pandemics that rapidly spread through-out the world, namely COVID-19 and antibiotic resistant bacteria (specifically, Carbapenemase Producing Bacteria -CPE- that populate patient’s gut).
Projects are financed, among others, by the US Department Of Defense, US Department of Homeland Security, the Israeli Ministry Of Defense and the Horizon 2020 SME program of the European Union.
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